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differential rheumatology management hematology vasculitis causes comparison diseases erythematosus joint lung oncology pain table vasculitides abpa activation algorithm allergic aspergillosis
Eosinophilia - Differential Diagnosis Algorithm Idiopathic Eosinophilia Primary Eosinophilia: • Primary hypereosinophilic syndrome • Eosinophilic Leukemia • MPN/MDS
Diagnosis Algorithm ... GI, lung, skin), ... B-cell lymphomas), Systemic ... , Sarcoidosis, SLE ... IBD Stanford Internal
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
- Differential Diagnosis ... Rhinitis - Allergic ... Lymphomas - Systemic ... Hypereosinophilic Syndrome ... #Causes #hematology
Approach to Eosinophilic Lung Diseases • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
loss, malaise • Allergic ... Hypereosinophilic Syndrome ... loss; CV, CNS, skin ... Lung #Diseases #pulmonary ... #differential #diagnosis
Interstitial Lung Diseases (ILD) Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): • Hypersensitivity pneumonitis, Farmer's lung, Bird
a.k.a. extrinsic allergic ... Tissue Disease: • Systemic ... Polymyositis-dermatomyositis, Lupus ... Churg Strauss syndrome ... #diagnosis #differential
Small Vessel Vasculitides • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
and C viruses. systemic ... lupus erythematosus ... and Sjogren's syndrome ... in absence of skin ... #differential #diagnosis
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Amyloidosis • Eosinophilic ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #differential #diagnosis
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Associated with skin ... block • Sjogren syndrome ... Treatment: • Mild ... diagnosis #rheumatology
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
PSS: Sjogren syndrome ... rheumatoid arthritis SLE ... : systemic lupus ... ConnectiveTissueDiseases #ILD ... Comparison #Table #Pulmonary
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Wilson's disease Pulmonary ... • Pulmonary ... Scleroderma Thickened skin ... Amyloidosis • Eosinophilic ... #differential #diagnosis
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
and Systemic Symptoms ... Skin involvement ... withdrawal • Mild ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
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