22 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Syndrome (SS), ... (SLE), Systemic ... (SLE), Systemic ... Lymphoproliferative Disorders
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Disease: Discoid lupus ... , Loose anagen syndrome ... Examination: • Signs ... Vitamin D levels Systemic ... Differential #Diagnosis #dermatology
Mucous Membrane Disorder - Differential Diagnosis Algorithm
Erosions/Ulcers/Blisters
 - Primary Dermatologic Diseases
     •
Mucous Membrane Disorder ... Differential Diagnosis Algorithm ... necrolysis - Systemic ... lupus erythematosus ... • Squamous cell
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Differential Diagnosis Algorithm ... of Lumbar Spine and ... arthritis - (Reiter’s syndrome ... Lupus - with Systemic ... (SLE), should have
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
Differential Diagnosis Algorithm ... • Loose anagen syndrome ... • Discoid lupus ... #dermatology #Differential ... #Diagnosis #Algorithm
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Female • Peaks 3rd ... permanent alopecia ... • Nonscarring alopecia ... #Systemic #Lupus
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... areas -> Scaring alopecia ... • Red plaques ... UV light Incr cell ... pathophysiology #diagnosis #signs
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... Abnormality • SLE ... • Nephrotic syndrome ... #Secondary #dermatology ... Differential #Diagnosis #Algorithm
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Physical Exam/Signs ... Scoring system: ... lymphoproliferative disorders ... AIHA • Pure red
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
arteritis, Cogan's Syndrome ... Arthritis (RA), Systemic ... lupus erythematosus ... (SLE), Sarcoidosis ... Cancer, Histiocytic disorders