20 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... • Immunologic Workup ... Positive in 60-80% of cases ... life-threatening • Treatment ... #lupus #Systemic
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Discontinuation of causal ... months to years) Systemic ... • Immunologic Workup ... Usual therapeutic management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... of Systemic Lupus ... Erythematosus (SLE ... autoantibodies that will cause ... cerebritis #diagnosis #management
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Associated with skin manifestations ... severe disease Treatment ... #Lupus #Erythematosus ... #rheumatology #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lupus erythematosus ... lupus erythematosus ... [SLE], AOSD) • ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia
Unexplained increase in ETCO2 AND tachycardia AND increased
other, more common causes ... Change breathing system ... Anesthesiology #Anesthesia ... Checklist #Diagnosis #Management ... #Workup
Intraoperative Hypertension - Guidelines for Crises in Anaesthesia
Hypertension is most commonly due to inappropriate depth of
entire breathing system ... hypercarbia as causes ... be diagnostic – see ... Checklist #Diagnosis #Management ... #Workup
Intraoperative Bronchospasm - Guidelines for Crises in Anaesthesia

❶ Call for help and inform theatre team of
perform a rapid systematic ... suspected airway see ... Anesthesiology #Anesthesia ... Checklist #Diagnosis #Management ... #Workup
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
trolley, anaphylaxis treatment ... hypotension. ❻ If systolic ... Anesthesiology #Anesthesia ... Checklist #Diagnosis #Management ... #Workup
Cardiac Arrest - Guidelines for Crises in Anaesthesia

The probable cause is one or more of: something
Check breathing system ... • See Boxes B ... Anesthesiology #Anesthesia ... Checklist #Diagnosis #Management ... #Workup