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diagnosis differential rheumatology management algorithm oncology causes signs skinrash symptoms syndrome clinical comparison erythematosus leukemia photo table thrombocytopenia vasculitis activation
Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
identification of red-flags ... to exclude dermatologic ... sulfa-drug - Skin ... #Diagnosis #Dermatology ... #Rash #Maculopapular
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... • SLE • Human ... lesions • Discoid lupus ... Sarcoidosis #dermatology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... UV light Incr cell ... inflammation on skin ... Manifestations #pathophysiology ... signs #symptoms #complications
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Thrombocytopenia #Lupus ... #SLE #systemic
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis Malar rash: • A
Combination of Skin ... Suggestive of: Lupus ... Suggestive of: Lupus ... Suggestive of systemic ... gabrieltalledop #dermatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Female • Peaks 3rd ... Decade Skin ... Seizures • Strokes Skin ... #Systemic #Lupus
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Hepatomegaly • Skin ... Scoring system: ... AIHA • Pure red ... workup #oncology #hematology
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions - Inflammatory
Vesiculobullous Skin ... Rash - Differential ... • Bullous systemic ... lupus erythematous ... Vesiculobullous #SkinRash #dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
lymphocytic lymphoma (SLL ... -> Invade Skin: ... Transformation: • Complication ... Lymphocytic Lymphoma (SLL ... #Leukemia #Hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Epidemiology: -10% of all ... NPSLE rare, Malar rash ... months to years) Systemic ... Manifestations: Malar rash ... #table #rheumatology
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