12 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Epidemiology: -10% of all ... Constitutional symptoms ... Workup: - ANA ... months to years) Systemic ... #table #rheumatology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Scaring alopecia • Red ... UV light Incr cell ... Manifestations #pathophysiology ... diagnosis #signs #symptoms
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
rendering the immune system ... non-Hodgkin lymphoma SLL ... with no early symptoms ... Scoring system: ... AIHA • Pure red
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
- Local and systemic ... - Red blood cell ... systemic lupus ... Classification #Pathophysiology ... Diagnosis #Reactions #Table
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... findings (ANA, ... Female • Peaks 3rd ... : • Symptoms limited ... #Systemic #Lupus
Glaucoma - Emergency Department Management
- All patients should get emergency ophthalmologic consultation
- Start with eye drops
- All patients ... with eye drops (see ... table below) and ... add systemic medications ... or refractory symptoms
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Symptoms: - Fever ... general feeling of ill ... development of skin symptoms ... ’s syndrome - Lupus ... Syndrome #diagnosis #dermatology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Management Summary ... survival is 93-95% Pathophysiology ... and increased B-cell ... the lymphatic system ... skin (16-32%): lupus
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... • Induce blast cell ... Diagnosis: >3 symptoms ... coagulopathy, RRT ... APML #diagnosis #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... Central nervous system ... Biologic: 2nd or 3rd ... Rheumatology #Diagnosis #Management