25 results
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Reactive: • Anemia/blood ... Post-splenectomy or Asplenia ... Differential #Diagnosis #causes ... #Platelets #hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Causes of Splenomegaly ... Hepatic, Portal, Splenic ... Spherocytosis • Acquired causes ... Diagnosis #Algorithm #Causes ... #Hematology
Acute Purpura Fulminans Skin Rash on Physical Exam 
60 year old male ITP s/p splenectomy 
1d
rigors, diarrhea, nausea ... Vibrio, aeromonas, Capnocytophaga ... in setting of asplenia ... Your blood cxs identify ... BIDMC Infectious Diseases
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
dogs & latter can cause ... gram-negative bacillus cause ... underlying r.f as asplenia ... patients who are asplenic ... University Infectious Diseases
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... • Nonmalignant hematologic ... : Acute blood loss ... Vasculitides, IBD, Celiac disease ... period • Others: Asplenia
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Causes of False ... deficiency • Asplenia ... turnover • Acute blood ... End-stage renal disease
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... Common d/t impaired splenic ... Pain #SickleCell #Disease ... #hematology
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
Causes of Ascites ... thrombosis • Splenic ... • Infiltrative disease ... Diagnosis #Algorithm #Hepatology ... #causes
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
• Infiltrative diseases ... Veno-occlusive disease ... thrombosis • Splenic ... Differential #Diagnosis #causes ... #hepatology
Chronic Abdominal Pain Causes - Differential Diagnosis Framework

Many patients with chronic abdominal pain have had prior
Abdominal Pain Causes ... the patient • Blood ... genitourinary causes ... Splenomegaly/Abscess • Splenic ... vein thrombus • Splenic