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diagnosis hematology algorithm management causes chronic classification lymphoma workup apml bandemia cbc cell ckd cll comparison deficiency differentiation diffuse disease
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Hodgkin's Lymphoma ... involvement Differential ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Lymphadenopathy - Differential ... Biopsy • Non-Hodgkin's ... Biopsy • Hodgkin's ... Algorithm #Causes #Hematology ... #Oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm Hodgkin ... Depletion Non-Hodgkin ... Classification #pathophysiology ... #Hematology #Diagnosis ... #NonHodgkin #differential
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
identical to the non-Hodgkin ... • Neutropenia, anemia ... PML leukemia, Hodgkin ... diagnosis #workup #oncology ... #hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview ... Neutrophil (Normal) Differential ... #differential # ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
have hemolytic anemia ... mobilize folate stores ... depleted tissue stores ... deficiency #FolicAcid #differential ... #diagnosis #hematology
Anemia of Chronic Disease - Pathophysiology One theory to explain why "anemia of chronic disease" exists: The inflammatory
Anemia of Chronic ... Disease - Pathophysiology ... to lock up iron stores ... #disease #hematology ... #pathophysiology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... initiation • Differential ... diagnosis #management #hematology ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Pinpoint-sized red spots ... • Aplastic Anemia ... blood count with differential ... Syndromes #diagnosis #hematology ... #oncology
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