15 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Initial screening test ... severe disease Treatment ... Hydroxychloroquine *Short ... Summary #diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Puncture, EEG Treatment ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... diagnosis #management #treatment
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Focal LN (<50% of glomeruli ... Diffuse LN (>50% of glomeruli ... Nephritis #Management #treatment ... #management #rheumatology ... #nephrology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal Syndrome ... Complex: Systemic lupus ... sclerosis • Anti-Glomerular ... , biopsy By Tess ... differential #diagnosis #nephrology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... • Hepatitis B serology ... Arthritis #laboratory #workup ... diagnosis #testing #Rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... Liver function tests ... Treatment: • Corticosteroids ... #Rheumatology
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... Spot PC (protein ... C3, C4 - Test for ... #testing #workup ... nephrotic #nephritic #nephrology
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... Spot PC (protein ... . 5) C3, C4 - Test ... #workup #diagnosis ... initial #testing #nephrology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... Positive pathergy test ... is a skin prick test ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitis - Skin, glomeruli ... : - Kidneys: glomerular ... such as systemic lupus ... retinopathy Lab Tests ... differential #diagnosis #rheumatology