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rheumatology management dermatology erythematosus lupus causes differential generalized pruritus signs symptoms activation ana antinuclear autoantibodies behcet cerebritis chronic classification cll
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Abnormality • SLE ... • Nephrotic syndrome ... #Secondary #dermatology ... #Differential #Diagnosis ... #Algorithm #causes
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Demyelinating syndromes ... ) Blood (75%): Anemia ... signs #symptoms #diagnosis ... #rheumatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Algorithm - Systemic ... renal failure/uremia ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #Diagnosis #Algorithm
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Classified among the secondary ... erythematosus [SLE ... with leukopenia, anemia ... #Diagnosis #Management ... #Hematology #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Erythematosus (SLE ... ) Clinical Manifestations ... Demyelinating Syndrome ... APS), Secondary
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
antibodies and Systemic ... is clinically suspected ... overlap syndromes ... erythematosus #diagnosis ... table #ANA
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... : • Clinical triad ... Type III Often Secondary ... Labs/Diagnosis: ... erythematosus (SLE
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Differential Diagnosis ... Clinical Features ... lymphopenia, low PLT • Anemia
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
renal failure/uremia ... Myelodisplastic syndrome ... #Pruritus #secondary ... #systemic #generalized ... #Diagnosis #Algorithm
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... Venous disease (SVC ... (Clinical Dx). ... Oral aphthae : SLE ... • Arthritis: SLE
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