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Vasopressors Demystified

Shock comes in many flavors and so do vasopressors. Here’s a OnePager summarizing my approach
Vasopressors Demystified ... Shock comes ... #Basics #CriticalCare ... #Management #Pharmacology ... #Comparison #Inotropes
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
Vasopressors and ... #Inotropes #management ... #criticalcare # ... summary #comparison ... #pharmacology #indications
Overview of Ventilator Modes
VC - Volume Control (a.k.a. assist control volume)
 - Every breath delivered (mandatory
triggered) is the same set ... triggered ) is a set ... pressure (IP) for a set ... #CriticalCare # ... Comparison #Management
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
Vasopressors and ... first agent in shock ... line in septic shock ... Pharmacology #Summary #management ... #medications
Pressors and Inotropes

Norepinephrine
 • alpha1 > beta 1
 • Increase SVR > Inotropy
Vasopressin
 • V1
 •
1 • Increase SVR ... 1 • Increase SVR ... Pressors #Inotropes #criticalcare ... #pharmacology #comparison ... #shock #management
Intern Pocket Cards - Daily Rounding and Disposition Checklist
Daily Checklist:
 • FEN/GI:
[ ] Upcoming procedure ... intake (including medications ... review daily) • DVT ... On mechanical ventilator ... Disposition #Checklist #management
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... High CO / Low SVR ... Failure, Toxins/Medications ... Differential #Diagnosis #criticalcare ... algorithm #treatment #management
Shock - Diagnosis and Management Summary
 • Hypotension: SBP<90, SBP drop >40, MAP<65 (Normotension, HTN possible
and Management ... Prepare • Full Set ... Neurogenic >> Vasopressors ... #Diagnosis #Management ... #Summary #criticalcare
Systemic Inflammatory Response Syndrome (SIRS)
•	Non-specific (infections vs non-infectious)
•	≥2 of the following:
o	Temp >38°C or <36°C
o	HR >90 bpm
o	RR
Septic Shock • ... >2 mmol/L Management ... (oxygenation, ventilation ... glycemic control, DVT ... #sepsis #sirs #shock
Clinical Management for Three Common Causes of Shock 
HEMORRHAGIC SHOCK
 • Ensure adequate ventilation and oxygenation.
Clinical Management ... Ensure adequate ventilation ... • Begin vasopressor ... #Shock #Management ... #CriticalCare