9 results
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
Pericardial tamponade, Pulmonary ... pharmacology ... #pharmacology # ... inopressors #diagnosis #management ... #comparison #table
Pressors and Inotropes

Norepinephrine
 • alpha1 > beta 1
 • Increase SVR > Inotropy
Vasopressin
 • V1
 •
1 • Increase SVR ... Pressors #Inotropes #criticalcare ... #pharmacology # ... comparison #shock ... #management
Shock - Differential Diagnosis Framework
MAP = CO x SVR
Hypovolemic (↓ Intravascular volume):
 • Hemorrhage, dehydration due
Shock - Differential ... dehydration due to renal ... adrenal crisis, drugs ... Diagnosis #table #comparison ... #criticalcare
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... Failure, Toxins/Medications ... • Obstructive: Pulmonary ... Differential #Diagnosis #criticalcare ... algorithm #treatment #management
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
Vasopressors #Inotropes #management ... #criticalcare # ... summary #comparison ... #table #pharmacology ... #indications
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
and Inotropes - Pharmacology ... first agent in shock ... 2 mcg/kg/min): renal ... #Summary #management ... #medications
Approach to Undifferentiated Shock - OnePager Summary
Shock occurs when there is inadequate blood flow (CO) &
Cardiac Tamponade, Pulmonary ... Pipes Problem (↓ SVR ... thyrotoxicosis), Medications ... albumin, trauma), Renal ... guyton #curves #criticalcare
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... Torsemide) • Acute pulmonary ... • Hypovolemic shock ... Diuresis #Nephrology #Pharmacology ... #Medications #Table
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
, bradycardia. renal ... A dissociative drug ... No pharmacologic ... Delirium #PAD #ICU #CriticalCare ... #diagnosis #management