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Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
for workup of thrombocytopenia ... /HUS indicates thrombotic ... thrombocytopenic ... , Hematology 2012 ... , p 193 #Diagnosis
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... distinction has HUGE treatment ... and first-line treatment ... #Comparison #Diagnosis ... #Table #Hematology
Treatment Algorithm for First Time DVT
 • Provoked
 • Unprovoked
 • Active Malignancy

By Carlin Rooke, MD.

#DVT
Treatment Algorithm ... for First Time DVT ... #DVT #Treatment ... Algorithm #management #hematology ... #VTE #thrombosis
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
- Differential Diagnosis ... Thrombocytopenic ... Toxin-Mediated HUS (ST-HUS ... Microangiopathy #TMA #hematology ... #differential #diagnosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... effect following treatment ... following EtOH induced thrombocytopenia ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Treatment of Thrombotic ... Thrombocytopenic ... Purpura (TTP) Diagnosis ... #Thrombocytopenic ... hematology
Approach to suspected Heparin-Induced Thrombocytopenia (HIT)

 • Suspected HIT Algorithm
 • "4 T's" clinical probability score:
Heparin-Induced Thrombocytopenia ... score: - Thrombocytopenia ... - Thrombosis ... #HIT #hematology ... #diagnosis #4Ts
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
 - PFO: paradoxical emboli
 - Popliteal
- Differential Diagnosis ... compression and DVT ... APLS:PLT ↓ HEMATOLOGIC ... #Differential #Diagnosis ... #clots #hematology
4-T Score for the Likelihood of Heparin Induced Thrombocytopenia
 - Thrombocytopenia - Compare the highest platelet
count
- Thrombocytopenia ... platelet fall or thrombosis ... ) - Thrombosis ... #Likelihood #Diagnosis ... #Hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Heparin Induced Thrombocytopenia ... (HIT) - Diagnosis ... 5-10d, venous (DVT ... Diagnosis: • ... #Treatment #Hematology