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Hemolytic Anemia - Hemolysis Diagnostic Workup

Infographic by: Howard Ong

#Hemolysis #Hemolytic #Anemia #Algorithm #MAHA #TTP #Diagnosis #Workup
Hemolytic Anemia ... - Hemolysis Diagnostic ... Algorithm #MAHA #TTP ... #Diagnosis #Workup ... #Hematology
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... : • Thrombotic ... microangiopathies (TMA) - TTP ... syndrome (ST-HUS ... #hematology #hemolysis
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... and first-line treatment ... #Thrombotic ... thrombocytopenia #Comparison #Diagnosis ... #Table #Hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
- Differential Diagnosis ... TableThrombotic ... Thrombocytopenic Purpura (TTP ... Toxin-Mediated HUS (ST-HUS ... Microangiopathy #TMA #hematology
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
 - PFO: paradoxical emboli
 - Popliteal
- Differential Diagnosis ... compression and DVT ... MALIGNANCY: - TMA: TTP ... HIT - MAHA: TTP ... #clots #hematology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... anticoagulants (DOACs ... DVT = deep vein ... thrombosis; PE = ... Anticoagulation #Management #Hematology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Treatment of Thrombotic ... ) Diagnosis of ... HUS) Treatment ... is diagnosed, in ... hematology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
TTP/HUS indicates ... thrombotic thrombocytopenic ... purpura/hemolytic ... thrombocytopenia, Hematology ... 2012, p 193 #Diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... syndrome - Thrombotic ... microangiopathy: Thrombotic ... thrombocytopenic purpura (TTP ... #hematology #anemia
Treatment Algorithm for First Time DVT
 • Provoked
 • Unprovoked
 • Active Malignancy

By Carlin Rooke, MD.

#DVT
Treatment Algorithm ... for First Time DVT ... #DVT #Treatment ... Algorithm #management #hematology ... #VTE #thrombosis