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hematology management erythematosus sle systemic antiphospholipid differential thrombocytopenia activation algorithm ana anticoagulation antinuclear apls aps associations autoantibodies behcet cerebritis cns
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... vasculopathy, thrombosis ... permeability Diagnosis ... CNS #neurology #rheumatology
Thrombotic Microangiopathy - TTP VS HUS Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... and first-line treatment ... thrombocytopenia #Comparison ... #Diagnosis #Table ... #Hematology
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
PSS: Sjogren syndrome ... SLE : systemic lupus ... #Differential #Comparison ... #Table #Pulmonary ... #Rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... Non-autoimmune rheumatologic ... Clinical Features ... #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
5-10d, venous (DVT ... : • Clinical Suspicion ... non-heparin A/C if clinical ... #Management #Treatment ... #Hematology #HemeOnc
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
-15% If SLE is clinically ... SLE-SSc-AlM overlap syndromes ... erythematosus #diagnosis ... #rheumatology # ... table #ANA
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... antibodies (aPL): • Lupus ... at least: • 1 clinical ... or small-vessel thrombosis ... to be present Treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Organomegaly+↑RBC/plt+, ↑thrombosis ... to cold IgG • Lupus ... Hyperviscosity (Thrombosis ... beds-renal, retinal, DVT ... #Differential #Diagnosis
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