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Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Thrombotic Microangiopathies ... In Systemic Lupus ... Erythematosus #SLE ... #hematology #rheumatology ... #differential #diagnosis
Treatment Algorithm for First Time DVT
 • Provoked
 • Unprovoked
 • Active Malignancy

By Carlin Rooke, MD.

#DVT
Treatment Algorithm ... #DVT #Treatment ... #Algorithm #management ... #hematology #VTE ... #thrombosis #venous
Disorders of the Hepatic and Mesenteric Circulation

Platelets in Cirrhosis
Hypercoagulability in Cirrhosis
Bleeding in Cirrhosis
Portal Vein Thrombosis (PVT)
Mesenteric
Cirrhosis Portal Vein Thrombosis ... Vein Thrombosis ... Circulation #Disorders #Hepatology ... Gastroenterology #diagnosis ... #Management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Erythematosus (SLE ... vasculopathy, thrombosis ... Erythematosus #SLE ... #management #treatment
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... life-threatening • Treatment ... #lupus #Systemic ... #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... severe disease Treatment ... #Summary #diagnosis ... #rheumatology # ... management
Portal Vein Thrombosis (PVT) Treatment Algorithm
 - If concern for ischemic: anti-coag+multidisciplinary care
 - W/o cirrhosis+recent
Portal Vein Thrombosis ... (PVT) Treatment ... #PVT #Treatment ... #management #Algorithm ... #hepatology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Treatment of Thrombotic ... Purpura (TTP) Diagnosis ... Thrombocytopenic #Purpura #management ... #treatment #rheumatology ... #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
and Management ... 5-10d, venous (DVT ... Confirmatory test ↑Se ... #Management #Treatment ... #Hematology #HemeOnc
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... DVT = deep vein ... thrombosis; PE = ... Anticoagulation #Management ... #Hematology #Oncology