11 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... , Headache, Movement ... vasculopathy, thrombosis ... permeability Diagnosis ... #management #treatment
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... PNS and CNS • Headache ... : • Symptoms limited ... : • Chronic B-cell ... Erythematosus #Diagnosis
Emergent Causes of Headache and Associated Risk Factors
Carbon monoxide poisoning
 - Breathing in enclosed or confined
with the same symptoms ... (eg, systemic lupus ... Cerebral venous sinus thrombosis ... vasoconstriction syndrome ... differential #emergency #diagnosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... • Treatment: ... • Evolution: Chronic ... #sle #comparison ... #rheumatology #diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
(headache and diplopia ... , dural sinus thrombosis ... Arthritis, AS Treatment ... Recurrent and chronic ... #signs #symptoms
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
characterized by: • Headache ... mental status • Headache ... Neurological symptoms ... Cerebral venous thrombosis ... epilepticus Treatment
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Fatigue - Headaches ... - Lupus - Leukemia ... cutis Diagnosis ... Treatment: - Systemic ... #diagnosis #dermatology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
(ET) ET is a chronic ... When present, symptoms ... • "Vasomotor" symptoms ... — Headache, visual ... MI, stroke, DVT/
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
decompression SVC ... : CNS changes, headache ... : CNS changes, headache ... → no immediate treatment ... Oncology #HemeOnc #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Eosinophilia, asthma, chronic ... inflammation Others: • Lupus ... - Thrombosis ... such as systemic lupus ... Presentation - Systemic Symptoms