946 results
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Injury: • Hepatic ... Venoocclusive disease • Hepatic ... salts augment synthesis ... ALP - Due to synthesis ... source - Tests of synthetic
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
g/dl (suggest hepatic ... • Preserved hepatic ... synthetic function ... sarcoidosis) • Liver ... metastasis • Fatty liver
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Laboratory Findings in Hepatic ... / Liver Failure ... Decreased albumin synthesis ... fold with acute liver ... #LiverFailure #Hepatic
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... Identify Acute Liver ... salts augment synthesis ... ALP - Due to synthesis ... replaced by non-hepatic
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Pre-analytical cause (e.g. heparin ... thrombin inhibitors, heparin ... Decreased factor synthesis ... • Reduced liver ... synthesis (impaired
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Early liver disease ... unfractionated heparin ... cause e.g. heparin ... Decreased factor synthesis ... Reduced liver synthesis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
dysfunction (25%) • Hepatic ... DIC • Severe Liver ... : - Impaired synthesis ... deficiency) • HIT: Heparin-PF4 ... 100mg/dL) - Heparin
Functions of the Liver

Storage 
Degradation 
Metabolism 
Synthesis 

#Pathophysiology #Functions #Liver #Hepatology #Synthesis #Storage #Metabolism
Functions of the Liver ... Metabolism Synthesis ... Pathophysiology #Functions #Liver ... #Hepatology #Synthesis
Hepatic Masses on MRI - Differential Diagnosis by MRI Findings

Masses: Hemangioma, Adenoma, FNH, HCC, Fibrolamellar HCC,
Hepatic Masses on ... Venous, Delayed, Hepato-Biliary ... CBarreraMD #Hepatic ... differential #diagnosis #liver
Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Sequestrants → ↓ Hepatic ... Acid Pool → ↑ Hepatic ... Bile Acid Synthesis