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diagnosis management infections differential infectiousdiseases opportunistic syndrome capsulatum coagulation dic disseminated fungal hemophagocytic histoplasmosis hiv hivaids hlh idsa immune inflammatory
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... should be based on clinical ... Antimicrobial treatment ... Demyelinating disease caused ... Syphilis • Aspergillosis
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
with or without treatment ... , but without treatment ... resembling rashes caused ... Rash #Diagnosis #Clinical ... #Photo #Dermatology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... without other cause ... : 33% • Treatment ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... Thromboembolism (7%) • CNS ... : • Treat primary ... cause • Correct ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
Lymphohistiocytosis (HLH) Treatment ... Primary HLH: - ... (depending on CNS ... autoimmune disease, treatment ... #management #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... • 8%-27% for CNS ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment
IDSA Recommendations for Preventing and Treating Histoplasma Capsulatum Infections in HIV-AIDS Indications for Initiating Primary Prophylaxis: •
Preventing and Treating Histoplasma ... Infections in HIV-AIDS ... histoplasmosis (>10 cases ... weeks or until clinically ... IDSA #Prevention #Treatment
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
of HIV/AIDS patients ... be present: • AIDS ... initiation Clinical ... pleural effusions, CNS ... Bartonella henselae • Histoplasma
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
Diagnosis: • Histoplasma ... has five major clinical ... yeast • At risk: AIDS ... especially the CNS ... MC: CNS CSF: •
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