15 results
Cellular and humoral immune responses of the adaptive immune system. Activated T cells accomplish cellular immune
Activated T cells ... to the T-cell receptor ... histocompatibility complex ... depending on the T-cell ... ImmuneResponses #immunology #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
with cytotoxic T ... Antigen-antibody complexes ... erythematosus Type IV - T ... and cytotoxic T ... Classification #Pathophysiology
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
other tissue • T ... to CD4+ helper T ... B cellsT cell-independent ... co-receptor complex ... Humoral #Immunity #pathophysiology
Systemic Lupus Erythematosus (SLE): Pathogenesis

 • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
dysfunction of dendritic cells ... , B-cells, T-cells ... production of immune complexes ... Auto-reactive T-cells ... Erythematosus #SLE #Pathophysiology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm
Physical:
 • Trauma
 • Pressure
 • Radiation
Vascular:
 • Arterial
Differential Diagnosis Algorithm ... : • Squamous cell ... fungoides (cutaneous T-cell ... Viral - Herpes simplex ... Differential #Diagnosis #Algorithm
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Erythroderma - Diagnostic Algorithm ... Pathophysiology: ... germinative skin cells ... 4) Skin-homing T-cells ... Erythroderma #Nikolsky #Algorithm
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... as common - T ... Cell ~10% - B-Cell ... Classification #pathophysiology ... #differential #algorithm
An intuitive way to use ultrasound to evaluate sick patients along the peri-shock to full shock
I call it, “Think ... #Diagnosis #POCUS ... #Evaluation #Protocol ... #Algorithm #High
An intuitive way to use ultrasound to evaluate sick patients along the peri-shock to full shock
I call it, “Think ... #Diagnosis #POCUS ... #Evaluation #Protocol ... #Algorithm #Low
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Activation of CD8 T ... cells (IFN-y) → ... Hemopathies+++: Hodgkin, T-cell ... inhibitors under evaluation