12 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
with cytotoxic T ... IV - T cells - ... and cytotoxic T ... #Classification ... #Pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
it is entirely T-Cell ... exposure to allergen causes ... allergen-specific T-Cell ... exposure, because T-Cell ... Allergy #Immunology #pathophysiology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Allergen-specific lgE causes ... - Mediators: T ... Th1/cytotoxic T ... T-cells recruit ... allergy #table #classification
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Erythroderma - Diagnostic Algorithm ... Pathophysiology: ... germinative skin cells ... Causes: 1) Exfoliative ... 4) Skin-homing T-cells
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... as common - T ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #differential #algorithm
Pathogenesis of Rheumatic Fever

Pathogenesis of rheumatic fever. 
1. GAS pharyngitis leads to antigenic presentation of pathogenic
pathogenic peptides to T-cells ... cross-reactive T-cells ... This facilitates T-cell ... Exposure of Type-IV ... antibodies which can cause
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
surfaces causes ... it is entirely T-Cell ... allergen-specific T-Cell ... exposure, because T-Cell ... #Classification
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
e.g., uptake by cells ... / hypoxemia -> focus ... - Cyanide - Propofol ... #typea #typeb # ... classification
Retroviral Infections: Mechanisms of Oncogenesis
Note: A retrovirus is an RNA virus that uses reverse transcriptase to
RNA virus that uses ... others); • Human T-cell ... lymphotropic virus type ... 1 (Adult T-cell ... #oncogenesis #pathophysiology
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
Causes of Hyperkalemia ... renin-angiotensin-aldosterone axis; T ... Pseudohypoaldosteronism type ... High #Potassium #Classification ... #Causes