12 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
) Pathophysiology ... →Activation of CD8 ... IFN-y) → Excessive activation ... , Hb), Hepatic dysfunction ... Lymphohistiocytosis #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Lymphohistiocytosis (HLH ... excessive macrophage activation ... genetic immune dysfunction ... / Diagnosis: HLH ... Lymphohistiocytosis #diagnosis #management
Management of Abdominal Distension and Bloating - Treatment Algorithm

Definitions
Pathophysiology
Organic/Pathologic Etiologies:
 • Small Intestinal Bowel Overgrowth (SIBO)
Management of Abdominal ... Definitions Pathophysiology ... • Pelvic Floor Dysfunction ... • Functional ... Dyspepsia • Functional
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... lymphohistiocytosis (HLH ... nervous system (CNS) dysfunction ... thrombocytopenia • Liver function ... Syndrome #Diagnosis #Management
Functional Dyspepsia - Pathophysiology, Diagnosis and Management
Risk factors: Non-steroidal anti-inflammatory drugs, Psychological comorbidity, Helicobacter pylori infection,
Functional Dyspepsia ... - Pathophysiology ... Diagnosis and Management ... #Diagnosis #Management ... #algorithm #gastroenterology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... cytopenias and organ dysfunction ... Persistent fever, organ dysfunction ... Pathophysiology ... Impaired cytotoxic function
Systemic Lupus Erythematosus (SLE): Pathogenesis

 • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
(Mutations in HLA ... - DR2/HLA-DR3 genes ... defects (i.e. dysfunction ... self-antigens, activating ... Erythematosus #SLE #Pathophysiology
Irritable Bowel Syndrome (IBS) - Pathophysiology, Diagnosis and Management Algorithm
Risk factors: Previous acute enteric infection, Female
Syndrome (IBS) - Pathophysiology ... Diagnosis and Management ... Algorithm Risk ... Younger age, Other functional ... #Diagnosis #Management
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... • Pathophysiology ... cytokines, complement activation ... INITIAL MANAGEMENT ... ADVANCED MANAGEMENT
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bowel or bladder dysfunction ... monophasic Pathophysiology ... • Excessive activation ... Autonomic Dysfunction ... Myelitis #diagnosis #management