54 results
The Death Spiral: Increased RV Afterload (Acute PE) 
#Pathophysiology #PE #PulmonaryEmbolism #Embolism #DeathSpiral #Shock #RVDysfunction #RebelEM
RV Afterload (Acute ... PE) #Pathophysiology ... #DeathSpiral #Shock ... #RVDysfunction
Shock - Pathophysiology 
Inadequate tissue perfusion to meet O2, nutrient requirements
1. Distributive Shock
2. Hypovolemic Shock
3. Cardiogenic
Shock - Pathophysiology ... Hypovolemic Shock ... #Shock #Pathophysiology ... #differential #diagnosis ... #algorithm #causes
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
malignancy (Especially acute ... protein C and S Pathophysiology ... 64%) • Renal dysfunction ... (16%) • Shock ... #Coagulation #diagnosis
Bedside Classification of Shock

Hypovolemic shock 

- Vomiting, diarrhea, overdiuresis 

- Hemorrhage (GI, peritoneal, RP) 

Distributive shock
Hypovolemic shock ... cardiomyopathy Acute ... valve dysfunction ... Prosthetic valve dysfunction ... Comparison #Table #Diagnosis
Hypotension / Shock Differential Diagnosis Algorithm
Hypovolemic:
 • Poor oral intake
 • Hemorrhage
 • Renal loss
 •
Hypotension / Shock ... Differential Diagnosis ... Algorithm Hypovolemic ... #Differential #Diagnosis ... #Algorithm #shock
Causes of Pediatric Stridor - Differential Diagnosis Algorithm
Present Since Infancy with No Respiratory Distress:
 • Laryngomalacia
Present
- Differential Diagnosis ... Algorithm Present ... Stenosis Non-Acute ... Papillomatosis Acute ... #Algorithm #Causes
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... Pregnancy (AFLP) Pathophysiology ... hepatocytes → Liver dysfunction ... headache, malaise) → Acute ... rapidly develops (DIC
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm
ACTH-Dependent (Secondary):
 • Pituitary Dysfunction
 • Hypothalamic Dysfunction
ACTH-Independent (Primary):
- Differential Diagnosis ... Algorithm ACTH-Dependent ... : • Pituitary Dysfunction ... • Hypothalamic Dysfunction ... vein thrombosis), DIC
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... • Pathophysiology ... and sometimes DIC ... mental status DIAGNOSIS ... #Diagnosis #Management
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Post-partum • Acute ... DIC - Septic shock ... catastrophes, Acute ... table #comparison #diagnosis