10 results
Shock - Pathophysiology 
Inadequate tissue perfusion to meet O2, nutrient requirements
1. Distributive Shock
2. Hypovolemic Shock
3. Cardiogenic
Shock - Pathophysiology ... Hypovolemic Shock ... #Shock #Pathophysiology ... #differential # ... diagnosis #algorithm
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... 64%) • Renal dysfunction ... 25%) • Hepatic dysfunction ... • Respiratory dysfunction ... (16%) • Shock
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm
ACTH-Dependent (Secondary):
 • Pituitary Dysfunction
 • Hypothalamic Dysfunction
ACTH-Independent (Primary):
Insufficiency - Differential ... Diagnosis Algorithm ... : • Pituitary Dysfunction ... • Hypothalamic Dysfunction ... vein thrombosis), DIC
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... Life-threatening organ dysfunction ... cellular/metabolic dysfunction ... • Pathophysiology ... and sometimes DIC
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... hepatocytes → Liver dysfunction ... rapidly develops (DIC ... infiltration) Differential ... diagnosis #management #pathophysiology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Heat Stroke - Differential ... Collapse: • Pathophysiology ... cardiomyopathy, ARDS, DIC ... coagulopathy - Possible DIC ... heat #illness #differential
Orofacial Granulomatosis - Diagnosis and Management Algorithm
Idiopathic OFG: isolated swelling of the lips, BX+ non-caseating granuloma
Melkersson-Rosenthal
and Management Algorithm ... facial paralysis *Differential ... Syphilis, Cat-Scratch Dis ... Triamcinolone dental paste ... Resolve w Rx of IBD Algorithm
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Cord Disorders - Differential ... • Herniated disc ... Bowel and bladder dysfunction ... diagnosis #neurology #differential ... #algorithm
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Infection/Sepsis/Shock ... Etiology: • Pathophysiology ... unclear, endothelial dysfunction ... Reversible course Differential
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm
Structural Defect - Asplenia/HypospIenism
 • Bacteremia/Septic
Immunocompromised Host - Differential ... Diagnosis Algorithm ... Bacteremia/Septic Shock ... or Neutrophil Dysfunction ... #Diagnosis #Algorithm