12 results
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... • Pathophysiology ... • Symptoms: Fever ... INITIAL MANAGEMENT ... ADVANCED MANAGEMENT
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... 64%) • Renal dysfunction ... • Respiratory dysfunction ... (16%) • Shock ... causes #treatment #management
Management of Abdominal Distension and Bloating - Treatment Algorithm

Definitions
Pathophysiology
Organic/Pathologic Etiologies:
 • Small Intestinal Bowel Overgrowth (SIBO)
Management of Abdominal ... Bloating - Treatment Algorithm ... Definitions Pathophysiology ... • Pelvic Floor Dysfunction ... Distension #Bloating #Management
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Diagnosis and Management ... mucus, Abd pain, Fever ... Toxic Megacolon, Shock ... Perforation) Pathophysiology ... Ileus, Megacolon, Shock
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... : 1) T-cell dysfunction ... General: fever, ... Sarcoidosis #Diagnosis #Management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Subacute-Acute: • Common: fever ... severe APLS, organ dysfuxtion ... APML #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... • Clinical: fever ... , Hb), Hepatic dysfunction ... Lymphohistiocytosis #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Infection/Sepsis/Shock ... Etiology: • Pathophysiology ... unclear, endothelial dysfunction ... Syndrome #diagnosis #management
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm
Structural Defect - Asplenia/HypospIenism
 • Bacteremia/Septic
Causes of Fever ... Differential Diagnosis Algorithm ... Bacteremia/Septic Shock ... or Neutrophil Dysfunction ... Infection #Fever
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
or family - Ever ... event, follow ACC algorithm ... with valvular dysfunction ... or LV dysfunction ... medical and surgical management