31 results
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Laboratory Testing ... in Hemolytic Anemia ... #Laboratory #Testing ... #workup #diagnosis ... #hematology #hemolysis
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Hypoproliferative Macrocytic Anemia ... Hypothyroid • Liver Disease ... #Macrocytic #Anemia ... diagnosis #algorithm #hematology ... #workup
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Abnormal Coagulation Tests ... Abnormal #APTT #Laboratory ... #Hematology #Diagnosis ... #Workup
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Anemia - Underproduction ... Iron deficiency anemia ... chronic kidney disease ... Underproduction #Algorithm #hematology ... #differential #workup
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
breakdown • Anaemia ... Hemolysis #Hemolytic #Anemia ... Differential #Causes #Workup ... #Hematology #Diagnosis ... GrepMed Recommended Text
Gastrointestinal Evaluation of Iron Deficiency Anemia
In patients with anemia, diagnose iron deficiency if:
 • Ferritin <
Iron Deficiency Anemia ... • Additional laboratory ... disease with serology ... change medical management ... Gastrointestinal #Evaluation #workup
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
, Drugs, Liver Disease ... Defects: Sickle cell anemia ... Hypophostphatemia Laboratory ... Tests: - Haptoglobin ... Differential #Diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... hemolysis, deficiency anemia ... Vasculitides, IBD, Celiac disease ... Diagnosis #Algorithm #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
• Pancreatic Disease ... Liver Function Tests ... Liver Function Tests ... • Liver Disease ... Algorithm #Causes #Hematology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
inhibitor • Liver disease ... • Underfilled test ... Thromboplastin #laboratory ... #hematology #diagnosis