53 results
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Laboratory Testing ... in Hemolytic Anemia ... #Laboratory #Testing ... #workup #diagnosis ... #hematology #hemolysis
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Investigation of Abnormal ... Coagulation Tests ... #APTT #Laboratory ... #Hematology #Diagnosis ... #Workup
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
Study • Clotting tests ... can be abnormal ... Study #diagnosis #hematology ... pathophysiology #hematology ... #laboratory
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Hypoproliferative Macrocytic Anemia ... Hypothyroid • Liver Disease ... #Macrocytic #Anemia ... diagnosis #algorithm #hematology ... #workup
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Anemia - Underproduction ... Iron deficiency anemia ... chronic kidney disease ... Underproduction #Algorithm #hematology ... #differential #workup
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
breakdown • Anaemia ... Hemolysis #Hemolytic #Anemia ... Differential #Causes #Workup ... #Hematology #Diagnosis ... GrepMed Recommended Text
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Liver Function Tests ... Deficiency - Abnormal ... Liver Function Tests ... • Liver Disease ... Algorithm #Causes #Hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Defects: Sickle cell anemia ... Hypophostphatemia Laboratory ... Tests: - Haptoglobin ... Blood Smear ↑ abnormal ... Differential #Diagnosis #hematology
Gastrointestinal Evaluation of Iron Deficiency Anemia
In patients with anemia, diagnose iron deficiency if:
 • Ferritin <
Iron Deficiency Anemia ... • Additional laboratory ... disease with serology ... change medical management ... Gastrointestinal #Evaluation #workup
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... GI. uterine) Laboratory ... PT/INR • Normal ... VonWillebrand #Disease ... #Diagnosis #Hematology