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management differential hematology algorithm disease erythematosus sle oncology table ana antinuclear causes classification comparison disorders druginduced fungal infectiousdiseases renal signs
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... • Immunologic Workup ... life-threatening • Treatment ... #Summary #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Initial screening test ... severe disease Treatment ... #SLE #Summary #diagnosis ... #rheumatology #
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... Immune Complex: Systemic ... lupus erythematosus ... Disease-specific testing ... , biopsy By Tess
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Demyelinating Syndrome ... permeability Diagnosis ... CNS #neurology #rheumatology ... #cerebritis #diagnosis
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
calcinosis • Pulmonary ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #symptoms #testing ... #workup
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
PSS: Sjogren syndrome ... lupus. ... LungDisease #CTILD #Diagnosis ... Comparison #Table #Pulmonary ... #Rheumatology #
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
during medical evaluation ... or workup for specific ... 1,500 cells/µL Workup ... glucocorticoid treatment ... #Differential #diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... Liver function tests ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... months to years) Systemic ... • Immunologic Workup ... comparison #table #rheumatology ... #diagnosis #management
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... , Interstitial Pulmonary ... ANA #patterns #rheumatology ... #diagnosis #differential
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