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diagnosis differential hematology neurology algorithm anemia apls arterial cryofibrinogenemia disorders embolism extravascular hemolysis hemolytic hp hypercoagulable hypertrophic intravascular management manifestations
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Nephrotic Syndrome ... Malignancy - Antiphospholipid ... considered in all cases ... coagulation and other causes ... pathophysiology #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... - Thrombotic ... microangiopathy: Thrombotic ... Hemolytic uremic syndrome
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Causes: 1. ... Supply: - AVM - Antiphospholipid ... Spinal artery thrombosis ... MCTD, Sjogren syndrome ... disorders #diagnosis #neurology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
necrosis) - Thrombosis ... (Thrombotic vasculopathy ... cryoglobulins • Negative causes ... HUS and HIT • Antiphospholipid ... syndrome • Warfarin-induced
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid ... Syndrome (APLS) ... Hypercoagulable Workup ... or small-vessel thrombosis ... maternal chromosomal causes
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
meninges in spinal cord ... nerve roots Spinal Cord ... Reconstitution Inflammatory Syndrome ... infarction, vasospasm, thrombosis ... neurological symptoms • Caused
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Stiff Person Syndrome ... Prevalence: 1-2 cases ... brain and spinal cord ... antibody that works ... Management #treatment #neurology
Hypertrophic Pachymeningitis - Differential Diagnosis Framework Pachymeningitis is a rare condition that causes areas of a layer
condition that causes ... surrounds the spinal cord ... thickening can cause ... brain sagging syndrome ... Cerebral venous thrombosis
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