7 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Cathepsin G release → vascular ... Attempt if high risk ... common • Imaging: CXR ... - pulmonary opacities ... sepsis), PE, DAH, CHF
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
murmur 3/6) - Pulmonary ... disease b) CHF ... Change in clinical ... - Peripheral vascular ... stratification #diagnosis
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
factors: Critical ... : Age>60, CKD, CHF ... fluid balance, and CXR ... with pulmonary ... Reactions #hematology #diagnosis
Atrial Fibrillation (A-Fib) Summary

Symptoms:
• Palpitations, light-headedness, dizziness, dyspnea, exercise intolerance, chest pain, near-syncope, syncope.

Why?
Cardiac:
	• Valvular heart
Decompensated HF ... Noncardiac: • Pulmonary ... cardiovascular risk ... TEE to exclude thrombus ... Fibrillation #AFib #diagnosis
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
or dilated) • Valvular ... cardiomyopathy • Pulmonary ... LVEDd > 6.0 cm, LV thrombus ... Clinical • Under-recognized ... May have typical HF
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Hyperviscosity, - Vascular ... Cryofibrinogenemia Clinical ... thrombophlebitis, pulmonary ... emboli, and ocular thrombi ... : • + Clinical
Peripartum Cardiomyopathy (PPCM)

What is PPCM?
• A form of acute systolic heart failure that develops late in
Risk Factors: • ... Anemia ✗ NOT a risk ... Key Point: High clinical ... Relaxin: reduces vascular ... congestion on a CXR