25 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... • Reaction to Medications ... Diagnosis #Algorithm #hematology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Toxic: Alcohol, Medication ... , Recreational Drugs ... obstruction, HELLP Syndrome ... GVHD • Toxic: Medication ... #algorithm #hepatology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
response to the drug ... For most indications ... #pharmacology #treatment ... #medications #table ... decisionaid #cardiology #hematology
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
Indications for ... ascites removed • Acute ... • Hepatorenal syndrome ... Management #Cirrhosis #treatment ... #hepatology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Anticoagulant Medications ... Advanced Liver Disease ... catastrophes, Acute ... Deficiencies #Summary #table ... comparison #diagnosis #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
duration), Several medications ... /HDS treatments ... Alcohol-related liver disease ... dechallenge • Acute ... Diagnosis #Algorithm #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... underlying liver disease ... Hepatitis (AAH) Drug-Induced ... Failure #Cirrhosis #Hepatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Secondary Causes: - Drug ... Kasabach-Merritt syndrome ... - APLS • Acute ... spotted fever • Drug ... Differential #Diagnosis #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... ) • Sepsis • Drug-induced ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
• SJS/TEN • Acute ... : symptomatic treatment ... • Severe disease ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis