13 results
diagnosis algorithm management rheumatology differential anemia causes druginduced erythematosus injury liver oncology sle systemic activation acute ana antinuclear aplastic autoantibodies
Managing warfarin INR Warfarin dosage must be individualized according to the patient's response to the drug, and
response to the drug ... For most indications ... #pharmacology #treatment ... #medications #table ... decisionaid #cardiology #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... • Reaction to Medications ... Diagnosis #Algorithm #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... usually IgG) (e.g. lupus ... infection) - Drugs ... differential #diagnosis #hematology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Toxic: Alcohol, Medication ... , Recreational Drugs ... obstruction, HELLP Syndrome ... GVHD • Toxic: Medication ... Acute #algorithm #hepatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... SJIA], systemic lupus ... ) • Sepsis • Drug-induced ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... duration), Several medications ... /HDS treatments ... Alcohol-related liver disease ... Diagnosis #Algorithm #hepatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Malignancy (e.g. hematologic ... vein thrombosis Hematologic ... extremities Drug ... • Antihistone: Drug ... activation and/or medications
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... life-threatening • Treatment ... Evolution: Chronic disease ... sle #comparison #table ... #rheumatology #
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Association with disease ... SLE (60-70%) & drug-induced ... SLE-SSc-AlM overlap syndromes ... with auto-immune diseases ... #table #ANA
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Dyskeratosis congenita • Drugs ... - Cytotoxic drugs ... - Antithyroid medications ... aplastic anemia Treatment ... Anemia #oncology #hematology
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