29 results
Anti-infective stewardship, including tips for using anti-infectives wisely, criteria for stepdown from IV to PO dosage
for using anti-infectives ... PO dosage forms and ... #pharmacology #antibiotics ... #medications #table ... #treatment #drugs
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Systemic lupus erythematosus ... (MCTD), Drug-induced ... Systemic lupus erythematosus ... Lymphoproliferative Disorders, Infection ... #patterns #rheumatology
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
angiitis induced by drugs ... , malignomas, and ... infectious diseases ... systemic lupus erythematosus ... Vessels #Diagnosis #Rheumatology
Drugs Used for the Treatment of COVID-19 Infection

** Editor Note (from ophthalmology MD input) - Hydroxychloroquine/chloroquine
Drugs Used for the ... -19 Infection ... Even with macular disease ... #COVID19 #Pharmacology ... #Table #Management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... fibromyalgia) • Infections ... extremities Drug ... • Antihistone: Drug ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Auto-Antibodies: - ANA ... Lupus Mimickers: Drug-induced ... Other auto-immune, Infectious ... #differential #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... Adult-onset Still disease ... immune deficiency, Drugs ... Unknown cause Treatment ... #summary #rheumatology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
response to the drug ... management #algorithm #pharmacology ... #treatment #medications ... #table #pharmacotherapy ... decisionaid #cardiology #hematology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
of life Causes and ... Infections 2. ... Drugs 5. ... Urticaria #diagnosis #rheumatology ... #comparison #table
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Systemic lupus erythematosus ... SLE], AOSD) • Infection ... ) • Sepsis • Drug-induced ... Treatment: • Corticosteroids ... #Rheumatology