15 results
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Reactive: - Systemic ... Inflammatory • Systemic ... Lymphocytes) - Monoclonal ... Algorithm #Causes #Hematology ... #Oncology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Neurologic-Centered: (+) Systemic ... Cryoglobulinemia (-) Systemic ... Ig deposition disease ... Differential #Diagnosis #hematology ... #oncology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Congenital Diseases ... telomeropathy Cancer ... : • Leukemia • ... : • Systemic lupus ... Differential #Diagnosis #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... chemotherapy for low-risk disease ... fludarabine) 3) Monoclonal ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
- Summary Cancer ... cells can indicate disease ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
associated with systemic ... disease. ... Treatment: - Systemic ... Syndrome #diagnosis #dermatology ... #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Can Feature A Monoclonal ... • Heavy Chain disease ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... Chronic leukemia ... extramedullary disease ... lymphoid organs When Cancer ... #Hematology #Oncology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... tears, Ischemia, Leukemia ... Arthritis, AS Treatment ... : monoclonal TNF-aIpha ... signs #symptoms #rheumatology