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diagnosis hematology management oncology chronic cll differential hemolytic leukemia lymphocytic activation algorithm autoimmune causes erythematosus hemeonc hodgkins lupus lymphoma macrophage
Autoimmune Hemolytic Anemia (AIHA) Treatment Warm AIHA: 1) Steroids - 1-2 mg/kg prednisone daily • Until
Autoimmune Hemolytic Anemia ... (AIHA) Treatment ... esp if severe disease ... Polyclonal: - Infection ... #AIHA #Treatment
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Causes: • Liver disease ... Hypersplenism • AIHA ... drug induced • Infections ... Diagnosis #causes #classification ... #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
for workup, including ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... : Chronic infections
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
5) Symptoms of anemia ... Complications: 1) Infection ... cytopenias (ITP, AIHA ... chemotherapy for low-risk disease ... AIHA, PRCA) • Treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
A subset of hemophagocytic ... SLE], AOSD) • Infection ... with leukopenia, anemia ... Treatment: • Corticosteroids ... #Rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
weeks without infection ... cells can indicate disease ... • Neutropenia, anemia ... microglobulin Treatment ... Leukemia #diagnosis #workup
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... Non-autoimmune rheumatologic ... fibromyalgia) • Infections ... Hematologic: • AIHA ... lymphopenia, low PLT • Anemia
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Weight loss • Anemia ... Hodgkin Lymphoma Workup ... number of sites of disease ... Hodgkin Lymphoma Treatment
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... petechiae) • Frequent infections ... Myeloproliferative Disease ... • Parvovirus infection ... Workup: • Complete
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