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management diagnosis idsa opportunistic prevention hematology hemophagocytic lymphohistiocytosis capsulatum classification coccidiodomycosis hemeonc histoplasma histoplasmosis lymphoma microsporidiosis oncology sjogrens summary syndrome
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemopathies+++: Hodgkin ... • Autoimmune diseases ... Adult-onset Still disease ... Treatment: • ... #summary #rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... History of EBV infection ... number of sites of disease ... Lymphoma Treatment ... classification #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
) Treatment Primary ... associated with infection ... or autoimmune disease ... for refractory disease ... #hematology
IDSA Recommendations for Treating Coccidiodomycosis in HIV-AIDS Treating Mild Infections (Such As Focal Pneumonia or asymptomatic patients
Treating Mild Infections ... with positive serology ... Extrathoracic Disseminated Disease ... IDSA #Prevention #Treatment ... #HIVAIDS #pharmacology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome caused ... Triggers: ▪ Infections ... ▪ Autoimmune diseases ... underlying trigger: Infections ... Diagnosis #Management #Hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Malignancy Risk: • Non-Hodgkins ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology
IDSA Recommendations for Preventing and Treating Varicella Zoster Virus (VZV) Infections in HIV-AIDS Pre-Exposure Prevention of VZV
confirmation of disease ... vaccination results in disease ... vaccine virus, treatment ... Uncomplicated Cases ... #HIVAIDS #pharmacology
IDSA Recommendations for Preventing and Managing Microsporidiosis in HIV-AIDS Preventing Chronic Microsporidiosis: • Because chronic microsporidiosis occurs
should prevent the disease ... Caused by Enterocytozoon ... : • The best treatment ... IDSA #Prevention #Treatment ... #HIVAIDS #pharmacology
IDSA Recommendations for Preventing and Treating Histoplasma Capsulatum Infections in HIV-AIDS Indications for Initiating Primary Prophylaxis: •
Histoplasma Capsulatum Infections ... histoplasmosis (>10 cases ... Severe Disseminated Disease ... IDSA #Prevention #Treatment ... #HIVAIDS #pharmacology
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