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diagnosis hematology management causes oncology erythematosus pulmonary sle systemic abscess activation algorithm associations chronic cll comparison connectivetissuediseases extravascular hemolysis hemolytic
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
PSS: Sjogren syndrome ... SLE : systemic lupus ... #LungDisease #CTILD ... #Diagnosis #Differential ... #Comparison #Table
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... Treatment: • ... #Systemic #Lupus ... #diagnosis #rheumatology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Congenital Diseases ... deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... : • Systemic lupus ... #Diagnosis #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... usually IgG) (e.g. lupus ... Extravascular #Causes #differential ... #anemia
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
hemolysis, deficiency anemia ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... SJIA], systemic lupus ... with leukopenia, anemia ... Treatment: • Corticosteroids ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... Shrinking lung syndrome ... lymphopenia, low PLT • Anemia ... Erythematosus #Diagnosis #Rheumatology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
and Management Summary ... Leukocytosis, anemia ... shows a small, stable ... Lung Abscess Differential ... Abscess #pulmonary #differential
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... (-) hemolytic anemia ... to cold IgG • Lupus ... Sneddon-Wilkinson disease ... #Monoclonal #Differential
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myeloproliferative Disease ... factor (GCSF) treatments ... blood count with differential ... marrow studies Treatment ... #diagnosis #hematology
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