15 results
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
), RA, crystal disease ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup ... #differential #
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... Diagnosis #Algorithm #hematology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Disease: • Pain ... disease must be ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Fever/Chills/Joint ... Infection - Systemic ... Effusions: - Hematologic ... #diagnosis #msk
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
site in lymphatic system ... with lymphatic system ... Responsive to Treatment ... Amy Chung, MD, MSc ... pathophysiology #Hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... and pain of the joints ... , breast CA - Hematologic ... Treatment: - Systemic ... Syndrome #diagnosis #dermatology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... frequently affected systems ... Better call hematology ... As with many disease ... #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic ... Resolution > 15 days Differentials ... : symptomatic treatment ... • Severe disease ... DRESS #Syndrome #dermatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... Scleromyxedema (CNS+GI+CVS+joints ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
caused by the inability ... Then, ask 3 questions ... to work through ... approach to the differential ... vaptans (HF/liver disease