8 results
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Thromboembolism (7%) • CNS ... • Severe Liver Disease ... Treat primary cause ... #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Cerebrovascular Disease ... , PRES Pathophysiology ... autoantibodies that will cause ... #neurology #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... • Nephrogenic DI ... phenomenon (16%) MSK ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Loss of teeth Anemia ... nonimmune hemolysis MSK ... , or any other cause ... Henoch-Schonlein purpura • DIC ... vasculitis Treatment
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... involvement • 30%: CNS ... -> AML: Blast crises ... - infiltrates (anemia ... Fibrinolysis & DIC
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... that results in CNS ... super-antigen mediated disease ... MCTD - Bechet disease ... Transverse Myelitis Treatment
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
dermatitis, a disease ... #diagnosis #causes ... on Surfactant Deposition ... Arch Dis Child. ... Pedersen MS, Benros
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome caused ... ▪ Autoimmune diseases ... - Cytopenias (anemia ... Pathophysiology ... Diagnosis #Management #Hematology