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differential management anemia blood hemolysis infectiousdiseases product algorithm autoimmune babesia causes extravascular fever intravascular microbiology platelets rheumatology thrombocytosis transfusion transfusions
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... 1) DIAGNOSE AIHA ... C3d • Blood smear ... Pouchelon #Warm #Antibody ... #Anemia #diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Other: Transfusion reaction ... Infections: Malaria, Babesiosis ... #differential #diagnosis ... #hematology #anemia
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... AIHA, Transfusion reactions ... toxins: Malaria, Babesiosis ... Peripheral Blood Smear ... #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Peripheral Smear ... blood loss, Acute hemolysis ... syndrome, POEMS • Reaction ... #Differential #Diagnosis
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Febrile Non-Hemolytic ... Hemolysis on labs ... Chagas disease), Babesiosis ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... Hemolysis on labs ... Chagas disease), Babesiosis ... #Transfusions #diagnosis ... #management #hematology
Babesiosis - Diagnosis and Management Summary Disease: Release of merozoites from erythrocytes and associated loss of
Babesiosis - Diagnosis ... integrity causing hemolysis ... renal failure Diagnosis ... • Thin blood smear ... identification • IgM antibody
Fever After International Travel Infectious Disease: • Endemic in either the destination or home region Viral Syndromes: Arboviral infections, a
No hemolytic anemia ... trypanosomiasis • Babesiosis ... cases of malaria diagnosed ... polymerase-chain-reaction ... chest film; blood-smear
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