12 results
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Antibody Autoimmune Hemolytic ... C3d • Blood smear ... : Differential → ... 2) LOOK FOR a cause ... management #treatment #rheumatology
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
neutrophil in a case ... acute myeloid leukemia ... neutrophils #AML #Clinical ... #Hematology #Pathology ... #Smear
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... features in most cases ... promyelocytic #leukemia ... APML #Pathology #Hematology ... #Clinical #Smear
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
- Differential ... • Lymphoma • Leukemia ... Serum Sickness Hemolytic ... Spleen #Enlarged #Differential ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... - Differential ... iron deficiency, hemolysis ... Chronic myeloid leukemia ... #hematology #secondary
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
decrease in most cases ... Peripheral blood smear ... WBC count and differential ... hematuria (without casts ... Diagnosis #Workup #Hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... Diagnosis: • hemolytic ... IgM) • Blood smear ... younger pts) Differential ... #anemia #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
promyelocytic leukemia ... organ damage Clinical ... • Peripheral smear ... Treat primary cause ... treatment #management #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... C4) • ds-DNA: Kidney ... Hodgkin lymphoma and leukemia ... Erythematosus #Diagnosis #Rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... • Hairy Cell Leukemia ... blood count with differential ... Peripheral blood smear ... Syndromes #diagnosis #hematology