11 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... myalgia, serositis, Kidney ... sle #comparison #table ... #rheumatology # ... diagnosis #management
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Peripheral Smear ... for workup, including ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Glucocorticoids, IL
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... of SLE versus DIL ... • Immunologic Workup ... life-threatening • Treatment ... Management #Summary #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... • Peripheral smear ... + Bleeding Treatment ... #Coagulation #diagnosis ... #causes #treatment
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
Related Disease Clinical ... lesions, meninges, kidneys ... with response to treatment ... management #phenotypes #workup ... #treatment #rheumatology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Dermatomyositis Clinical ... nephrotoxicity to kidney ... per day until stable ... #nephrology
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... myalgia, serositis, Kidney ... • Immunologic Workup ... #rheumatology # ... diagnosis #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Fever is the main clinical ... Heart, lung, and kidney ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Peripheral smear ... microglobulin Treatment ... #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Peripheral Smear ... Workup: • Complete ... Peripheral blood smear ... Myelodysplastic #Syndromes #diagnosis