63 results
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... (TLS) Tumor Cell ... -> Allantoin (High ... #TLS #Pathophysiology
Amenorrhea - Differential Diagnosis Algorithm
Elevated FSH
 • Premature Ovarian Failure
 • Menopa use
 • Spontaneous
Bleed With
Polycystic Ovarian Syndrome ... Abnormalities High ... Inflammatory Lesion • Tumors ... Diagnosis #Algorithm #endocrinology ... #causes
Hirsutism & Virilization - Differential Diagnosis Algorithm
ADRENAL EXCESS
Ovarian
 • Polycystic Ovarian Syndrome
 • Hyperthecosis
 • Tumor
Adrenal
Hyperthecosis • Tumor ... • Cushing's Syndrome ... Tumor Low Serum ... Diagnosis #Algorithm #endocrinology ... #causes
Breast Discharge - Differential Diagnosis Algorithm
High Prolactin + Normal TSH
 • Microprolactinoma
 • Steroid Hormone Intake
Diagnosis Algorithm High ... • Bronchogenic Tumor ... Prolactin + High ... Diagnosis #Algorithm #Endocrinology ... #Causes
Hypoglycemia Workup and Differential Diagnosis
Workup:
 • Sulfonylurea Labs
 • Anti-lnsulin Ab - Insulin Autoimmune Syndrome
 •
Insulin Autoimmune Syndrome ... with high tumor ... metabolic demand causes ... Insulin Autoimmune Syndrome ... Diagnosis #insulinoma #endocrinology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... immature blasts and high ... WBC count cause ... • Pathophysiology ... Spontaneous if high
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
SAME, Cushing Syndrome ... • HTN, High Aldosterone ... Renin secreting tumor ... , Gitelman syndrom ... Diagnosis #Algorithm #causes
Gynecomastia - Differential Diagnosis Algorithm
No Testicular Mass on Ultrasound
 • Adrenal Neoplasm
 • Increased Extraglomerular Aromatase
• Leydig Cell Tumor ... Klinefelter's Syndrome ... • Kallman's Syndrome ... Diagnosis #Algorithm #causes ... #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... neuroendocrine tumors ... Carpal Tunnel Syndrome ... signs #symptoms #endocrinology ... #pathophysiology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Diuretics (late) • High ... , Gitelman Syndrome ... hyperaldosteronism • High ... Renin-secreting tumor ... Algorithm #Nephrology #Causes