15 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... leukapheresis - TLS ... • Pathophysiology ... #TLS #diagnosis ... #management #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
basal ganglia, CNS ... Medium and large also ... interferon alfa, or tumor ... #diagnosis #management ... signs #symptoms #rheumatology
Hypoxemia / Hypoxia - Rapid Response Management Algorithm

Stridor - Upper airway pathology:
 • Anaphylaxis
 • Foreign
Rapid Response Management ... e.g., hematoma, tumor ... asthma • Pleural disease ... Hypoventilation: • CNS ... e.g., GBS, MG, ALS
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Cerebrovascular Disease ... , PRES Pathophysiology ... cerebritis #diagnosis #management
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Lateral Sclerosis (ALS ... ) Summary ALS: combination ... lateral sclerosis Pathophysiology ... (1) limb-onset ALS ... neurology #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
cytokines, such as ... nervous system (CNS ... tests ↑ AST ↑ ALT ... #Diagnosis #Management ... #Hematology #Rheumatology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
antibiotics TLS ... (tumor-lysis syndrome ... ): - Hematologic ... low Ca - q8 h TLS ... ) - Symptoms: CNS
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... involvement • 30%: CNS ... Fibrinolysis & DIC • Tumor ... lysis syndrome: ... #Leukemia #Hematology
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Cushing's Syndrome ... skin with stretch marks ... same precursor as ... #Cushings #Syndrome ... signs #symptoms #endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
malignancy Pathophysiology ... pancreatic islet cell tumor ... Beckwith Wiedemann syndrome ... levels not useful as ... #Endocrinology