14 results
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
polymorphisms alter ... Circulating galactose-deficient ... IgA1 (GD-IgA1). ... Deficiency in galactosylation ... HenochScholeinPurpura #Pathophysiology
Pathophysiology of Iron Deficiency in CKD

Dr. Muner Mohamed @MunerMohamed1

#Iron #Deficiency #CKD #Pathophysiology #nephrology
Pathophysiology ... of Iron Deficiency ... in CKD Dr. ... MunerMohamed1 #Iron #Deficiency ... #CKD #Pathophysiology
Causes of B12 deficiency. 

This great diagram shows normal absorption and outlines most possible causes. At
Causes of B12 deficiency ... the top is a B12-deficient ... HC, releasing Cbl ... #VitaminB12 #deficiency ... Causes #Diagnosis #Pathophysiology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
antibodies) -> Complete deficiency ... undetectable levels of IgA ... , IgG, and IgM ... Agammaglobulinemia #XLinked #pathophysiology
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
Fatigue and IBD ... Pearls: • IDA ... and active IBD: ... differentiate IDA ... restricted diet/deficiency
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Disease • GH Deficiency ... • IGF-I Deficiency ... Celiac, IBD) •
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Protein S deficiency ... - Protein C deficiency ... - Antithrombin deficiency ... Ischemic Liver, IBD ... Venous #Arterial #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Mortality due to CVD ... malignancy Pathophysiology ... stimulates liver IGF ... Workup: • Serum IGF ... Endocrinology #Treatment #Pathophysiology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Splenomegaly - CTD ... necrosis) • VIT K deficiency ... vasculitis • Ig ... EGPA - MPA • CTD
Celiac Disease - Diagnosis Algorithm
IgA TTG has high sensitivity and specificity of ~ 98% and is
Diagnosis Algorithm IgA ... for evaluating CD ... IgA deficiency affects ... 2%–3% of CD patients ... If IgA def --->