33 results
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Algorithm Symptoms ... quadrant discomfort Signs ... of autoimmune disease ... PBC if 2/3 criteria ... #Algorithm #hepatology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Criteria: • Elevated ... incidentally via CBC ... , signs, and complications ... von Willebrand disease ... #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Signs and Symptoms ... but elevated as disease ... Diagnosis: • ... , IgG4 related disease ... #workup #hepatology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... Vmphocytosis on routine CBC ... chemotherapy for low-risk disease ... #oncology #hematology ... #hemeonc #diagnosis
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... Symptomatic anemia Diagnosis ... to MDS or acute leukemia ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... Artifact (redo CBC ... Chronic Myelogenous Leukemia ... disorders • Celiac disease ... effect following treatment
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Lymphocytosis on CBC ... cells can indicate disease ... microglobulin Treatment
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... extramedullary disease ... count ↑ PLT • ↑ PBS ... #Hematology #Oncology ... #Diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... Signs and symptoms ... criteria for MS ... Multiple Sclerosis Treatment ... management #neurology #treatment