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diagnosis differential injury causes ascites transaminitis alcoholic chronic hbv hepatitisb saag aclf aflp aih albumin autoimmune chemistry cirrhosis dili disease
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Liver Failure ( ... months without treatment ... (DILI) Viral Hepatitis ... #Hepatology #gastroenterology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... > 20x normal - Acute ... cirrhosis, Portal Vein ... #Injury #hepatology ... #LFTs #transaminitis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... , Acute biliary ... Vasculature • Hepatic Vein ... Diagnosis #Causes #Acute ... #algorithm #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
failure 1) Hepatocellular ... • Infections: Hepatitis ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
Supportive with treatment ... liver failure ... Liver transplant ... Hepatobiliary #hepatology ... #hepatitis #differential
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... viral hepatitis ... Liver Failure ( ... #differential #Hepatology ... transaminitis #LFTs
Alcoholic Hepatitis - Management Algorithm 1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... - Management Algorithm ... can be bridge to Liver ... #Management #Algorithm ... #treatment #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
Diagnosis and Management ... Algorithm • ... #HBV #Algorithm ... #Diagnosis #Management ... #Treatment #Hepatology
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... > 3 mg/dL) or acute ... liver failure ... #Indications #management ... #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... liver failure rapidly ... → Multiorgan failure ... Diagnosis: Viral Hepatitis ... #Pregnancy #hepatology
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