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Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Skin Rash - Differential ... foliaceus - Infectious ... Bullous systemic lupus ... erythematous ... Diagnosis #Algorithm #causes
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... parvovirus B19 infection ... Malar rash ... parvovirus B19 infection ... lesions • Discoid lupus
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... evidence of (fatigue, rash ... Photosensitive rash ... fibromyalgia) • Infections ... lymphoproliferative syndrome Clinical
SKIN RASHES 



Skin rashes can occur from a variety of factors, including infections, heat, allergens, immune
factors, including infections ... petechial/purpuric, erythematous ... rashes into these classes ... petechiae; #purpura; #rash ... ; #vesiculobullous
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... 69% - Malar rash ... Other auto-immune, Infectious ... diseases, Hematological ... #Erythematosus
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... Positive in 60-80% of cases ... Evolution: Chronic disease
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... everywhere) 2) A rash ... 6) An annular rash ... Unexplained fever, when infection ... #system #erythematosus
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
within 1 month of infection ... Polyarthritis • Systemic Lupus ... with Systemic Lupus ... Erythematosus ( ... like “butterfly rash
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
rapidly evolving rash ... marine microbiota & causes ... chronic liver disease ... Diseases Fellowship ... dermatology #legs #clinical
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
Rash is usually ... early localized disease ... presenting with erythematous ... called "Bazin's disease ... so-called fifth disease