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diagnosis nephrology differential management potassium blood hematology medications pharmacology product reactions binders binding comparison diuresis diuretics ecg ekg evaluation excretion
Hyperkalemia shortens repolarization; changes in the T wave provide the earliest clues to hyperpotassemia. - At
Hyperkalemia shortens ... repolarization; changes ... – a sinusoidal waveform ... #EKG #ECG #Changes ... #Progression #Table
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
• Mechanism: Exchanges ... constipation, diarrhea, nausea ... ); nausea, vomiting ... patients sensitive to high ... #pharmacology #table
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... Food - Avoid in CRF ... kiwis, mangoes, oranges ... differential #diagnosis #causes ... #potassium #high
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... Food - Avoid in CRF ... kiwis, mangoes, oranges ... differential #diagnosis #causes ... #potassium #high
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm Reduced flow through distal nephron - TTKG
Causes of Hyperkalemia ... Differential Diagnosis Algorithm ... Low EABV (e.g., CHF ... • NSAlDs #Hyperkalemia ... #Causes
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Weakness, cramping, nausea ... Na delivery): CHF ... only if no clear cause ... Elimination (see Table ... K-Binding Resins - Exchanges
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based algorithm ... diuresis can be high ... : Hypovolemia, Hypervolemia ... differential #diagnosis #table
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Epidemiology 1) High ... -60y (hormonal changes ... hyperphosphatemia, hypercalcemia ... symptoms are not caused ... Self-limiting, chronic but stable
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Loop Diuretics; High-Ceiling ... Hyponatremia • Hypercalcemia ... Kidney stones caused ... Renal Epithelial Channels ... #Medications #Table
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
disease b) CHF ... ASA class If high ... event, follow ACC algorithm ... Change in clinical ... of Surgery: • High
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