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diagnosis rheumatology erythematosus hematology symptoms activation behcet cerebritis differential hemeonc hemophagocytic hlh lymphohistiocytosis neurology pathophysiology primary sjogrens tafro thrombocytopenia treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Syndrome (MAS) ... • Systemic lupus ... (CNS) dysfunction ... [SLE], AOSD) • ... #Management #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
of Systemic Lupus ... Demyelinating Syndrome ... Cerebrovascular Disease ... #SLE #CNS #neurology ... cerebritis #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... polyclinic or patchy papulosquamous ... (NPSLE): • May ... CNS • Headache ... #Systemic #Lupus
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... may be seen in ... (PBC), or with systemic ... lupus erythematosus ... (SLE) Signs /
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... Oral aphthae : SLE ... • Arthritis: SLE ... #diagnosis #management ... #signs #symptoms
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... purpura: Strong sign ... vasculitis • Behcet syndrome ... chorioretinitis, CNS ... vasculitis • Cogan syndrome
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
disorders, including systemic ... lupus erythematosus ... (SLE), Sjögren’ ... and the systemic ... TAFRO #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
of the immune system ... ▪ Autoimmune diseases ... (often termed MAS-HLH ... : Macrophage Activation ... Presentation • Common Signs
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