10 results
Antifungal Azoles - Antibiotics Class Overview

Mechanism:  inhibit ergosterol synthesis (important component of fungal cell membranes)
Antifungal Azoles ... - Antibiotics Class ... Overview Mechanism ... Isavuconazole(PO or IV) #Pharmacology ... #Overview #Azoles
Antifungal Polyenes - Amphoterecin B, Abelcet, Ambisome - Antibiotics Class Overview

Mechanism: binds ergosterol in membrane and
Antifungal Polyenes ... Abelcet, Ambisome - Antibiotics ... Class Overview ... #Pharmacology #Antibiotics ... #Review #Overview
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
Antifungal Echinocandins ... - Antibiotics ... Class Overview ... still usually works ... Anidulafungin #Pharmacology
Flutycosine - Antibiotics Class Overview
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Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
Flutycosine - Antibiotics ... Class Overview ... #Pharmacology #Antibiotics ... #Review #Overview ... #Flutycosine #Antifungal
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
trolley, anaphylaxis treatment ... Important culprits: antibiotics ... require prolonged treatment ... Anesthesiology #Anesthesia ... Diagnosis #Management #Workup
Overview of antifungal agents benefits, weaknesses, and adverse effects in the treatment of Coccidioidomycosis.
Fluconazole - Low
Overview of antifungal ... effects in the treatment ... valleyfever #management #treatment ... #antifungals #comparison ... #table #pharmacology
Macrolides - Erythromycin, Clarithromycin, Azithromycin - Antibiotics Class Overview

50S Ribosomal Inhibitor (PO and IV)
Spectrum: Atypical organisms
Azithromycin - Antibiotics ... Class Overview ... Used for MAC treatment ... #Pharmacology #Antibiotics ... #Review #Overview
Sulfonamides - Antibiotics Class Overview

BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic

Spectrum: Wide
Sulfonamides - Antibiotics ... Class Overview ... choice, both for treatment ... #Pharmacology #Antibiotics ... #Review #Overview
Anti-Pseudomonal - Antibiotics Class Overview

Pseudomonas aeruginosa is a non-fermenting Gram-negative bacillus that inhabits a variety of
Anti-Pseudomonal - Antibiotics ... Class Overview ... empiric Pseudomonas treatment ... Polymyxin B(IV) #Pharmacology ... #Overview #AntiPseudomonal
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... + empiric antifungal ... 500 → may stop antibiotics ... → no immediate treatment